Results 171 to 180 of about 1,399,462 (318)
Intensive care decision-making, survival and dying well: a mixed methods study with people who have been intensive care patients. [PDF]
Donaldson T, Keywood K, Frith L, Holm S.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Detection of mismatching visual kinematics during visuomotor incongruence: A comparison of spatially matched delays versus offsets along identical trajectories. [PDF]
Peters F, Wang P, Limanowski J.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Structure without semantics: no evidence for bonobo compositionality in Berthet et al. (2025). [PDF]
Wartel A +6 more
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The Quantity-Competence Presumption: Children Use Informativeness to Calibrate Trust and Infer Speakers' Knowledge. [PDF]
Bernard C, Depierreux A, Mascaro O.
europepmc +1 more source

