Results 241 to 250 of about 4,075,413 (333)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Public preferences for the value and implementation of genomic newborn screening: Insights from two discrete choice experiments in Australia. [PDF]

Am J Hum Genet
Peters R, Best S, Lynch F, Vears DF, Downie L, Archibald AD, Lunke S, Stark Z, Goranitis I.   +8 more
europepmc   +1 more source

Aeromagnetic map of the Magruder Mountain, Grapevine Canyon 2, and Ubehebe Crater quadrangles, and part of the Last Chance Range quadrangle, Nevada-California

, 1967

openalex   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Fair allocation of resources in the moral dilemma of triage. [PDF]

Front Sociol
Keßler P, Krumpal I.
europepmc   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Where's my mom? Resilient maternal preference in post-weaning male and female mice within a multi-chamber social behavior task. [PDF]

Brain Behav Immun Health
Slamin MM, Bishnoi IR, Bankowski IM, Norris HA, Bordt EA.   +4 more
europepmc   +1 more source

Beyond p‐values: Assessing clinical significance in acupuncture research

Advanced Chinese Medicine, EarlyView.
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley   +1 more source

Engaging youth to promote their well-being: methods and findings from a knowledge mobilization project in Nova Scotia, Canada. [PDF]

Res Involv Engagem
Kontak JC, MacRae C, Stronach L, Stymiest L, Kirk SFL.   +4 more
europepmc   +1 more source

Exploring what matters most to patients in relapsed refractory multiple myeloma treatment: a Canadian discrete choice experiment with patients, caregivers and physicians. [PDF]

BMC Cancer
Hall R, Chua GN, Macfarlane B, Plante RK, Shi K, Soltys S, McCurdy A, Elias M, Ranger J.   +8 more
europepmc   +1 more source