Results 11 to 20 of about 3,531 (146)

The regulation of bacterial two‐partner secretion systems

open access: yesMolecular Microbiology, Volume 120, Issue 2, Page 159-177, August 2023., 2023
Two‐partner secretion (TPS) systems play critical roles in bacterial pathogenesis by allowing the secretion of effector proteins such as cytolysins and adhesins. Here, we explore the diverse regulatory mechanisms that govern TPS system expression, including environmental stimuli, two‐component systems, quorum sensing, and global regulators, providing ...
Julian Trouillon   +2 more
wiley   +1 more source

Sonographic localisation and description of inguinofemoral lymph nodes in patients with vulvar squamous cell carcinoma

open access: yesSonography, Volume 10, Issue 2, Page 66-75, June 2023., 2023
Abstract Sonographic imaging of the inguinofemoral lymph nodes can be performed in patients with vulvar cancer to discriminate between normal (benign and reactive) and malignant appearing lymph nodes. A systematic sonographic protocol for imaging inguinofemoral lymph nodes is not commonly used, but could aid in homogenising the reporting of lymph node ...
Michelle Fenech
wiley   +1 more source

A review on monkeypox virus outbreak: New challenge for world

open access: yesHealth Science Reports, Volume 6, Issue 1, January 2023., 2023
Abstract Background Monkeypox is a viral zoonotic disease caused by the monkeypox virus, a double‐stranded DNA‐enveloped virus that can be transmitted from animal to human or human to human. Consequently, it emerged as the most important orthopoxvirus for public health.
Jannatul Ferdous   +4 more
wiley   +1 more source

A Comprehensive Review on HIV‐Associated Dermatologic Manifestations: From Epidemiology to Clinical Management

open access: yesInternational Journal of Microbiology, Volume 2023, Issue 1, 2023., 2023
Dermatological disorders are among the most prevalent manifestations of HIV infection/acquired immunodeficiency syndrome (AIDS). In this review, we aimed to characterize the various dermatologic presentations among HIV‐infected patients with a detailed categorization of the mucocutaneous signs and symptoms, their etiopathogenic factors, and clinical ...
Zeinab Mohseni Afshar   +8 more
wiley   +1 more source

Attitudes and Practices of the Use of Third‐Generation Cephalosporins among Medical Doctors Practicing in Cameroon

open access: yesInternational Journal of Clinical Practice, Volume 2023, Issue 1, 2023., 2023
Background. Third‐generation cephalosporins (3GC) are among the most prescribed antibiotics worldwide. Antibiotic resistance, usually due to misuse and overuse, is a feared complication of public health concern. However, there are limited data in Cameroon concerning the knowledge and use of 3GC in our health services.
Elisabeth Zeuko’o Menkem   +7 more
wiley   +1 more source

Sialic Acid 4‐N‐Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter

open access: yesChemMedChem, Volume 17, Issue 23, December 5, 2022., 2022
A new target: Bacterial sialic acid uptake inhibition is a promising strategy for the development of antibacterial drugs. In this study, we present the design, synthesis and evaluation of sialic acid 4‐piperidine and piperazine derivatives a novel compound class, which bind the SiaT from Proteus mirabilis and target a different portion of the binding ...
Tiago Bozzola   +3 more
wiley   +1 more source

The sexual health, orientation, and activity of autistic adolescents and adults

open access: yesAutism Research, Volume 14, Issue 11, Page 2342-2354, November 2021., 2021
Abstract Small studies suggest significant differences between autistic and nonautistic individuals regarding sexual orientation and behavior. We administered an anonymized, online survey to n = 2386 adults (n = 1183 autistic) aged 16–90 years to describe sexual activity, risk of sexually transmitted infections (STIs), and sexual orientation.
Elizabeth Weir   +2 more
wiley   +1 more source

Preference for daily versus on‐demand pre‐exposure prophylaxis for HIV and correlates among men who have sex with men: the China Real‐world Oral PrEP Demonstration study

open access: yesJournal of the International AIDS Society, Volume 24, Issue 2, February 2021., 2021
Abstract Introduction This study explores the preference for daily versus on‐demand pre‐exposure prophylaxis (PrEP) among men who have sex with men (MSM) in developing countries when both regimens are available. Methods From 11 December 2018 to 19 October 2019, we recruited MSM for an open‐label real‐world PrEP demonstration study in four major cities ...
Jing Zhang   +20 more
wiley   +1 more source

Adolescents’ Communication on Sexual and Reproductive Health Matters with Their Parents and Associated Factors among Secondary and Preparatory School Students in Ambo Town, Oromia, Ethiopia

open access: yesInternational Journal of Reproductive Medicine, Volume 2021, Issue 1, 2021., 2021
Background. Sexual and reproductive health (SRH) communication is most likely to promote healthy sexual practices and to reduce risky sexual behavior among adolescents. Communication is the principal means for parents to transmit sexual values and knowledge to their children.
Tesfaye Shibiru Bikila   +5 more
wiley   +1 more source

The Biology of the Cytolethal Distending Toxins

open access: yesToxins, 2011
The cytolethal distending toxins (CDTs), produced by a variety of Gram-negative pathogenic bacteria, are the first bacterial genotoxins described, since they cause DNA damage in the target cells. CDT is an A-B2 toxin, where the CdtA and CdtC subunits are
Teresa Frisan   +3 more
doaj   +1 more source

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