Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein [PDF]
FEBS Open BioThe Chandipura virus matrix protein plays a crucial role in virus assembly, budding, and the cytopathic effects observed in infected cells by interacting with several host proteins.
Mariana Grieben
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Elucidating the Interacting Domains of Chandipura Virus Nucleocapsid Protein [PDF]
Advances in Virology, 2013 The nucleocapsid (N) protein of Chandipura virus (CHPV) plays a crucial role in viral life cycle, besides being an important structural component of the virion through proper organization of its interactions with other viral proteins.
Kapila Kumar +8 more
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Chandipura Virus Causing Large Viral Encephalitis Outbreaks in India [PDF]
PathogensChandipura virus (CHPV) is a negative-, single-stranded RNA virus belonging to the family Rhabdoviridae [...]
Morgan E. Brisse, Hinh Ly
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Chandipura Virus Resurgence in India: Insights Into Diagnostic Tools, Antiviral Development, and Public Health Implications [PDF]
Global Health, Epidemiology and GenomicsConclusion: Despite considerable progress in diagnostics and experimental treatments, significant challenges remain in controlling CHPV outbreaks.
Adewunmi Akingbola +8 more
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Chandipura virus dysregulates the expression of hsa-miR-21-5p to activate NF-κB in human microglial cells [PDF]
Journal of Biomedical Science, 2021 Background Chandipura virus (CHPV) is a negative single-stranded RNA virus of the Rhabdoviridae family. CHPV infection has been reported in Central and Western India.
Neha Pandey +2 more
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Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo [PDF]
Molecular Therapy: Oncolytics, 2021 Chandipura virus (CHPV) is an emerging human pathogen of great clinical significance. In this study, we have investigated the susceptibility pattern of both normal and cancer cell lines of human origin to wild-type (wt) CHPV in order to explore the ...
Reshma Koolaparambil Mukesh +8 more
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Chandipura Virus infection in mice: the role of toll like receptor 4 in pathogenesis [PDF]
BMC Infectious Diseases, 2012 Background The susceptibility of mice and humans to Chandipura virus infection is age-dependent. Upon experimental infection, mice secrete significant amounts of proinflammatory cytokines.
Anukumar Balakrishnan, Shahir Prajakta
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Rational design of multi-epitope vaccine for Chandipura virus using an immunoinformatics approach [PDF]
PLoS ONEChandipura virus (CHPV) is endemic in India, with frequent outbreaks reported. No approved medicines or vaccines exist for CHPV. We aimed to develop a multi-epitope vaccine for CHPV using immunoinformatics approaches.
Ramtin Naderian +9 more
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Chandipura Virus Induced Neuronal Apoptosis via Calcium Signaling Mediated Oxidative Stress [PDF]
Frontiers in Microbiology, 2018 Chandipura Virus (CHPV) a negative-stranded RNA virus belonging to the Rhabdoviridae family, has been previously reported to bring about neuronal apoptosis by stimulating oxidative stress. Our in silico data suggested the involvement of Angiotensin II in
Abhishek K. Verma +2 more
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Analysis of the dark proteome of Chandipura virus reveals maximum propensity for intrinsic disorder in phosphoprotein [PDF]
Scientific Reports, 2021 Chandipura virus (CHPV, a member of the Rhabdoviridae family) is an emerging pathogen that causes rapidly progressing influenza-like illness and acute encephalitis often leading to coma and death of the human host.
Nishi R. Sharma +7 more
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