Results 201 to 210 of about 8,419,467 (214)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A reinforced lunar dynamo recorded by Chang'e-6 farside basalt. [PDF]

Nature
Cai S, Qi K, Yang S, Fang J, Shi P, Shen Z, Zhang M, Qin H, Zhang C, Li X, Chen F, Chen Y, Li J, He H, Deng C, Li C, Pan Y, Zhu R.   +17 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mesoscale Mechanisms Governing the Shear Strength of Lunar Regolith: Effects of Low Confining Stress and Irregular Particle Morphology. [PDF]

Materials (Basel)
Chen J, Li R, Ji Y, Mo P.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Lunar dichotomy in surface water storage of impact glass beads. [PDF]

Nat Commun
He H, Hu S, Gao L, Li R, Hao J, Mitchell RN, Lu K, Gao Y, Li L, Qiu M, Zhou Z, Yang W, Cai S, Chen Y, Jia L, Li QL, Hui H, Lin Y, Li XH, Wu FY.   +19 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Massive Water Production from Cryogenic Icy Lunar Regolith by a Microwave Heating Method. [PDF]

Research (Wash D C)
Wang Q, Pang Y, Gu J, Zhao Z, Sun Q, Yang M.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Magnetic signatures and origins of ferromagnetic minerals in Chang'e-6 lunar farside soils. [PDF]

Nat Commun
Li J, Xing L, Gong Z, Liu J, Liu Y, Wu W, Zhu K, Wang Y, Tang X, Gu L, Chen Y, Li Q, Cao Z, Liu S, Cai S, Pan Y.   +15 more
europepmc   +1 more source