Results 231 to 240 of about 2,624,164 (273)
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
2021
In situ TEM and other dynamic imaging instruments alter the landscape of materials science and engineering. The unique and unprecedented ability to observe the transformation of nanoscale objects as it occurs is unparalleled in comparison to other material characterization methods, and is of tremendous value to material scientists and engineers who ...
Chiwoo Park, Yu Ding
openaire +1 more source
In situ TEM and other dynamic imaging instruments alter the landscape of materials science and engineering. The unique and unprecedented ability to observe the transformation of nanoscale objects as it occurs is unparalleled in comparison to other material characterization methods, and is of tremendous value to material scientists and engineers who ...
Chiwoo Park, Yu Ding
openaire +1 more source
Multiscale Change Point Detection
Theory of Probability & Its Applications, 2017zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Suvorikova, A., Spokoiny, V.
openaire +2 more sources
Self-Normalized Sequential Change-point Detection
Statistica Sinica, 2021This article introduces a new sequential monitoring scheme for detecting change-points in general time series models which achieves an asymptotically exact Type-I error while at the same time it avoids estimation of the long-run variance. The key concept is the introduction of a self-normalizer (SN) to replace the long-run variance estimator when ...
Chan, Ngai Hang +2 more
openaire +2 more sources