Results 91 to 100 of about 9,693,328 (298)

A Report by the Climate Change Science Program and the Subcommittee on Global Change Research

, 2002
This document is a supplement to the President's Fiscal Year 2003 Budget. The report describes the activities and plans of the U.S. Global Change Research Program (USGCRP). The report also describes the start-up activities for the U.S.
Climate Change Science Program (U.S.)
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Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Seeds of Change

, 2008
How did the 20th century change the way Americans live? This ABC News program anchored by Peter Jennings examines daily life during the early 1900s--when William McKinley was President, a loaf of bread cost only a few cents, horsepower really meant ...

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The New Role of Business Education in Society

The Pinnacle
This article describes how business education can become a catalyst to drive societal development. Three solutions are provided. First, it is important to understand the learner today and what they may be experiencing in the future such as a dynamic ...
Bruce Stetar, Catherine McBride, David Gliddon, Cynthia Solari   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Our changing planet : the FY ... research plan

, 2000
Annual report of the U.S. Global Change Research Program documenting activities and progress, goals for the upcoming year, proposed budget considerations, and other information about the organization for fiscal year ...
U.S. Global Change Research Program
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Overview of the U. S. Climate Change Science Program [PDF]

, 2006
This is an overview fact-sheet for the U. S.
Climate Change Science Program (U.S.)
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The Family in Creating the National Security of Poland: Crisis or Evolution?

Roczniki Nauk Społecznych
The aim of this article is to discuss the importance of the family in creating the national security of Poland, taking into account its contemporary transformations, known as “crisis” and “evolution.” In order to achieve this, the image of the family in ...
Ilona Urych
doaj   +1 more source