Results 131 to 140 of about 9,693,328 (298)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Will Climate Change Affect Food Production?

open access: yes, 2010
How climate change may affect food systems in the Midwest?not peer reviewedSubmitted by Anthony Larson (alarson6@illinois.edu) on 2010-06-15T20:34:26Z No.
Wesley, Jarrell
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The batteries of change. Is your organisation energised for change

open access: yes, 2018
This white paper by Prof Peter De Prins, Prof Geert Letens and Prof Kurt Verweire sets out a new change model and outlines how you can use it to make lasting, effective change happen in your ...
Verweire, Kurt   +2 more
core  

Carbon Farming Initiative review [PDF]

open access: yes, 2014
SUMMARY The Authority is required by legislation to review the Carbon Farming Initiative (CFI) every three years; this is its first review. The review has benefited from consultations with stakeholders from a range of sectors and the Authority thanks ...
Climate Change Authority
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Global Climate Change Impacts in the United States [Highlights]

open access: yes, 2009
This booklet highlights key findings from the Global climate Change Impacts in the United States. a state of knowledge report about the observed and projected consequences of climate change for our nation and people.
U.S. Global Change Research Program
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Our changing planet : the FY ... research plan

open access: yes, 2002
Annual report of the U.S. Global Change Research Program documenting activities and progress, goals for the upcoming year, proposed budget considerations, and other information about the organization for fiscal year ...
U.S. Global Change Research Program
core  

Climate Change, Wildlife and Wildlands: A Toolkit for Formal and Informal Educators [PDF]

open access: yes, 2009
This brochure describes the effects of climate change in the desert and arid regions of the United ...
U.S. Global Change Research Program
core  

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