Results 161 to 170 of about 35,791,731 (317)

A Journey of Growth: Advancing the Future of [PDF]

open access: yes운동과학
Ji-Seok Kim, Jinkyung Cho, Hyuntae Park
doaj   +1 more source

Climate change 2001

open access: yes, 2001
James J. McCarthi   +4 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Climate change and youth in South Korea: A gendered analysis of psychosocial and behavioral profile. [PDF]

open access: yesJ Clim Chang Health
Lee EY   +5 more
europepmc   +1 more source

Change [PDF]

open access: yesJournal of Perioperative Practice, 2020
openaire   +2 more sources

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