Results 171 to 180 of about 3,919,259 (312)

SARCDNet-an enhanced deep learning network for change detection from bi-temporal SAR images. [PDF]

Sci Rep
Kevala VD, Mukundan V, Nedungatt S, Suresh S, Lal S.   +4 more
europepmc   +1 more source

Baci: Towards A Biosphere Atmosphere Change Index - Detection Of Extreme Events In The Biosphere

, 2018
Yanira Guanche García, Maha Shadaydeh, Miguel D. Mahecha, Markus Reichstein, Joachim Denzler   +4 more
openalex   +1 more source

REGIONAL-SCALE LANDSLIDE AND EROSION MONITORING UTILIZING AIRBORNE LIDAR CHANGE DETECTION ANALYSIS [PDF]

, 2017
A. Mitchell, Matthew Lato, Scott McDougall, Michael J. Porter, Stephanie Bale, Andrew Watson   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Spatial temporal fusion based features for enhanced remote sensing change detection. [PDF]

Sci Rep
Mugambi G, Rimiru R, Kimwele M, Muriuki C, Gakii C, Mukoya E.   +5 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Author Correction: ROBIN: Reference observatory of basins for international hydrological climate change detection. [PDF]

Sci Data
Turner S, Hannaford J, Barker LJ, Suman G, Killeen A, Armitage R, Chan W, Davies H, Griffin A, Kumar A, Dixon H, Albuquerque MTD, Ribeiro NA, Alvarez-Garreton C, Amoussou E, Arheimer B, Asano Y, Berezowski T, Bodian A, Boutaghane H, Capell R, Dakhlaoui H, Daňhelka J, Do HX, Ekkawatpanit C, El Khalki EM, Fleig AK, Fonseca R, Giraldo-Osorio JD, Goula ABT, Hanel M, Horton S, Kan C, Kingston DG, Laaha G, Laugesen R, Lopes W, Mager S, Rachdane M, Markonis Y, Medeiro L, Midgley G, Murphy C, O'Connor P, Pedersen AI, Pham HT, Piniewski M, Renard B, Saidi ME, Schmocker-Fackel P, Stahl K, Thyer M, Toucher M, Tramblay Y, Uusikivi J, Venegas-Cordero N, Visessri S, Watson A, Westra S, Whitfield PH.   +59 more
europepmc   +1 more source

Global change detection [PDF]

Nature, 1994
M.R. Alien, C.T. Mutlow, G.M.C. Blumberg, J.R. Christy, R.T. McNider, D.T. Llewellyn-Jones   +5 more
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source