Results 221 to 230 of about 3,919,259 (312)

Detection of changes in cartilage water content using MRI T2-mapping

, 2002
Carsten Liess, S. Lüsse, N. Karger, Martin Heller, C-C Glüer   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

ROBIN: Reference observatory of basins for international hydrological climate change detection. [PDF]

Sci Data
Turner S, Hannaford J, Barker LJ, Suman G, Killeen A, Armitage R, Chan W, Davies H, Griffin A, Kumar A, Dixon H, Albuquerque MTD, Almeida Ribeiro N, Alvarez-Garreton C, Amoussou E, Arheimer B, Asano Y, Berezowski T, Bodian A, Boutaghane H, Capell R, Dakhlaoui H, Daňhelka J, Do HX, Ekkawatpanit C, El Khalki EM, Fleig AK, Fonseca R, Giraldo-Osorio JD, Goula ABT, Hanel M, Horton S, Kan C, Kingston DG, Laaha G, Laugesen R, Lopes W, Mager S, Rachdane M, Markonis Y, Medeiro L, Midgley G, Murphy C, O'Connor P, Pedersen AI, Pham HT, Piniewski M, Renard B, Saidi ME, Schmocker-Fackel P, Stahl K, Thyer M, Toucher M, Tramblay Y, Uusikivi J, Venegas-Cordero N, Visessri S, Watson A, Westra S, Whitfield PH.   +59 more
europepmc   +1 more source

Change points detection - Applications in vegetation and temperature analysis

Niri, Rania
openalex   +1 more source

Change Detection of Desert Sand Dunes: A Remote Sensing Approach

, 2014
S Anand Kumar Varma, Vatsal Shah, Biplab Banerjee, Krishna Mohan Buddhiraju   +3 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Age-Related Differences in Neural Correlates of Auditory Spatial Change Detection in Real and Virtual Environments. [PDF]

Eur J Neurosci
Stodt B, Neudek D, Martin R, Wascher E, Getzmann S.   +4 more
europepmc   +1 more source

Analysis of Forest Change Detection Induced by Hurricane Helene Using Remote Sensing Data [PDF]

Rizwan Ahmed Ansari, Tony Esimaje, Oluwatosin Michael Ibrahim, Timothy Mulrooney   +3 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Recurrence Quantification Analysis for Scene Change Detection and Foreground/Background Segmentation in Videos. [PDF]

J Imaging
Kyprianidi T, Doutsi E, Tsakalides P.
europepmc   +1 more source