Results 41 to 50 of about 1,752,070 (218)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Dual-Branch Seasonal Error Elimination Change Detection Framework Using Target Image Feature Fusion Generator

Remote Sensing
In change detection tasks, seasonal variations in spectral characteristics and surface cover can negatively impact performance when comparing image pairs from different seasons.
Hongming Zhu, Jipeng Zhang, Zeju Wang, Xinyu Liu, Qin Liu, Bowen Du   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Rapid Fine-Grained Damage Assessment of Buildings on a Large Scale: A Case Study of the February 2023 Earthquake in Turkey

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
High-resolution stereo satellite images (HRSSIs) have the potential to provide the accurate height and volume information, playing a crucial role in assessing building collapses during various natural disasters.
Zhonghua Hong, Hongyang Zhang, Xiaohua Tong, Shijie Liu, Ruyan Zhou, Haiyan Pan, Yun Zhang, Yanling Han, Jing Wang, Shuhu Yang   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Extraction of Building Construction Time Using the LandTrendr Model With Monthly Landsat Time Series Data

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Extracting building construction time is crucial for effective land resource management and sustainable urban development, particularly in fast-growing urban areas.
Tengyun Hu, Meng Zhang, Xuecao Li, Tinghai Wu, Qiwei Ma, Jianneng Xiao, Xieqin Huang, Jinchen Guo, Yangchun Li, Donglie Liu   +9 more
doaj   +1 more source

Line-Constrained Shape Feature for Building Change Detection in VHR Remote Sensing Imagery

ISPRS International Journal of Geo-Information, 2018
Buildings represent the most relevant features of human activity in urban regions, but their change detection using very-high-resolution (VHR) remote sensing imagery is still a major challenge. Effective representation of the building is the key point in
Haifei Liu, Minhua Yang, Jie Chen, Jialiang Hou, Min Deng   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

High-Precision Heterogeneous Satellite Image Manipulation Localization: Feature Point Rules and Semantic Similarity Measurement

Remote Sensing
Misusing image tampering software makes it easier to manipulate satellite images, leading to a crisis of trust and security concerns in society. This study compares the inconsistencies between heterogeneous images to locate tampered areas and proposes a ...
Ruijie Wu, Wei Guo, Yi Liu, Chenhao Sun
doaj   +1 more source