Results 211 to 220 of about 10,617,293 (333)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Iterative smoothing for change-point regression function estimation. [PDF]

J Appl Stat
Thompson JRJ.
europepmc   +1 more source

A method to inform team sport training activity duration with change point analysis. [PDF]

PLoS One, 2022
Teune B, Woods C, Sweeting A, Inness M, Robertson S.   +4 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Methodological Innovation in Evaluating the Cost-Effectiveness of Simulation Training Combining Transfer Effectiveness and Change-Point Analysis. [PDF]

J Med Educ Curric Dev
Jiang Z, Hang H, Wu X, Xiang S, Pan S.
europepmc   +1 more source

High Dimensional Change Point Inference: Recent Developments and Extensions. [PDF]

J Multivar Anal, 2022
Liu B, Zhang X, Liu Y.
europepmc   +1 more source

Nonparametric multiple change-point estimation for analyzing large Hi-C data matrices [PDF]

, 2017
Vincent Brault, Sarah Ouadah, Laure Sansonnet, Céline Lévy‐Leduc   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Change point detection in brucellosis time series from 2010 to 2023 in Xinjiang China using the BEAST algorithm. [PDF]

Sci Rep
Yang L, Wang C, Zhou P, Xie N, Tian M, Wang K.   +5 more
europepmc   +1 more source

Lumpy Skin Disease Outbreaks in Africa, Europe, and Asia (2005-2022): Multiple Change Point Analysis and Time Series Forecast. [PDF]

Viruses, 2022
Anwar A, Na-Lampang K, Preyavichyapugdee N, Punyapornwithaya V.   +3 more
europepmc   +1 more source