This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Evolution of Liver Resection for Hepatocellular Carcinoma: Change Point Analysis of Textbook Outcome over Twenty Years. [PDF]
Park Y +9 more
europepmc +1 more source
A MULTIVARIATE SPATIOTEMPORAL CHANGE-POINT MODEL OF OPIOID OVERDOSE DEATHS IN OHIO. [PDF]
Hepler SA, Waller LA, Kline DM.
europepmc +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Change point detection to analyze air pollution and its economic effects: an exponentially weighted moving average perspective. [PDF]
Ahmad S, Riaz M, Mahmood T, Abbas N.
europepmc +1 more source
Detection and identification of cis-regulatory elements using change-point and classification algorithms. [PDF]
Maderazo D +4 more
europepmc +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Wild binary segmentation for multiple change-point detection [PDF]
Piotr Fryzlewicz
openalex +1 more source
A Selective Review on Information Criteria in Multiple Change Point Detection. [PDF]
Gao Z, Xiao X, Fang YP, Rao J, Mo H.
europepmc +1 more source
Asymptotic distributions of rank statistics in the change-point problem
F. Lombard
openalex +1 more source

