Results 61 to 70 of about 3,117,785 (309)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Application of Change-Point Detection to a Structural Component of Water Quality Variables

, 2011
In this study, methodologies were developed in statistical time series models, such as multivariate state-space models, to be applied to water quality variables in a river basin.
Gonçalves, A. Manuela, Costa, Marco, Marco Costa, Zacharias Anastassi, Theodore E. Simos, Ch. Tsitouras, A. Manuela Gonçalves, George Psihoyios   +7 more
core   +1 more source

Application of MCMC to change point detection [PDF]

, 2008
summary:A nonstandard approach to change point estimation is presented in this paper. Three models with random coefficients and Bayesian approach are used for modelling the year average temperatures measured in Prague Klementinum.
Legát, David, Antoch, Jaromír
core   +1 more source

Online change-point detection with kernels

Pattern Recognition, 2023
Change-points in time series data are usually defined as the time instants at which changes in their properties occur. Detecting change-points is critical in a number of applications as diverse as detecting credit card and insurance frauds, or intrusions into networks. Recently the authors introduced an online kernel-based change-point detection method
Ferrari, André, Richard, Cédric, Bourrier, Anthony, Bouchikhi, Ikram   +3 more
openaire   +4 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Change point detection in risk adjusted control charts

, 2011
Precise identification of the time when a change in a clinical process has occurred enables experts to identify a potential special cause more effectively. In this article, we develop change point estimation methods for a clinical dichotomous process in
Kerrie Mengersen, Mengersen, Kerrie, Assareh, Hassan, Smith, Ian, Ian Smith, Hassan Assareh   +5 more
core   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Establishing Climatic Change on Rainfall Trend, Variation and Change Point Pattern in Benin City, Nigeria

, 2023
This study examined the effect of changing climate for thirty-six years (1982-2017) on 24-hourly annual maximum time series (AMS) rainfall data for Benin City.
Sam, Masi G., Nwaogazie , Ify L., Ikebude, Chiedozie   +2 more
core   +1 more source

Using threshold Cox models to estimate change points in exposure-response relationships in an occupational epidemiological study of respirable crystalline silica and silicosis risk

Frontiers in Public Health
IntroductionIn occupational epidemiology, accurately quantifying exposure-response relationships is crucial.MethodsWe introduce a threshold Cox model that includes a change point term to identify the optimal threshold.
Diezhang Wu, Kenneth A. Mundt, Jing Qian
doaj   +1 more source

Assessing Contribution of Human Activities and Climate Variability on Groundwater Changes (Case Study: Mahidasht Aquifer, Kermanshah Province, Iran) [PDF]

محیط زیست و مهندسی آب
Revealing the contribution of each of the climatic and human factors can help the management of water resources. Firstly, trend analysis and change‐point tests were performed to determine the status of the parameters affecting the groundwater resources ...
Ali Fatahi Chaghabagi, Ali Mohammad Akhund Ali, Arash Azari   +2 more
doaj   +1 more source