Results 91 to 100 of about 961,218 (296)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Change Detection in Point Clouds Using 3D Fractal Dimension

open access: yesRemote Sensing
The management of large point clouds obtained by LiDAR sensors is an important topic in recent years due to the widespread use of this technology in a wide variety of applications and the increasing volume of data captured.
Juan C. Casas-Rosa   +7 more
doaj   +1 more source

Change-point detection by the SSA method

open access: yes, 2022
Software for masters thesis "Change-point detection by the SSA method"
Kononykhin, Ivan
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Change point Detection in Mortality Trend in IRAN

open access: yesمجله اپیدمیولوژی ایران, 2015
Background & Objectives: In the analysis of mortality trend in the Iran that is basically a sequences of observations sorted by time, there is a point where the statistical properties of the mortality trend change so that the first k0 observations have a
AR Baghestani, A Teymourpour, Y Bashiri
doaj  

Change-point detection for Lévy processes [PDF]

open access: yesThe Annals of Applied Probability, 2019
19 ...
Figueroa-López, José E.   +1 more
openaire   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Change Point Detection for Ocean Eddy Analysis

open access: yes, 2018
The detection and analysis of mesoscale ocean eddies is a complex task, made more difficult when simulated or observational ocean data are massive. We present the statistical approach of change point detection as a means to help scientists efficiently ...
Banesh, Divya   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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