Results 111 to 120 of about 15,871,401 (350)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
RETHINKING INDUSTRIAL POLICY [PDF]
Despite the hold of the neoliberal orthodoxy on policy making in developing countries, industrial policy remains important for the promotion of industrial development.
Irfan ul Haque
core
Strategic Interests in Australian Defence Policy: Some Historical and Methodological Reflections [PDF]
, 2015 The first, and often the hardest, step in any defence policy is to define strategic objectives—what we want our armed forces to be able to do. This is especially hard for a country like Australia, because most of the circumstances in which we would rely ...
White, Hugh
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
EDGES, EXPONENTIALS & EDUCATION: EXTENDING THE UNIVERSITY, DOING SCHOOL DIFFERENTLY
Tendencias Pedagógicas, 2015 The changed and changing circumstances of a world in which the performance of key technologies is improving at an exponential rate poses unique challenges to schooling systems that had their origins in the industrial revolution.
Leonie Rowan, Chris Bigum
doaj
Fighting austerity: Why after 80 years the General Theory is still relevant today, [PDF]
, 2017 The guiding spirit of the Keynesian Revolution is that full employment is a goal which can be pursued not by following the free market rules, but by reshaping them by means of public intervention.
Marcuzzo, Maria Cristina
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The impact of inter-organizational management control systems on performance: a longitudinal case study of a supplier relation in automotive. [PDF]
This study investigates whether appropriate management control design of supplier relations is associated with better performance. Although management control systems (MCSs) are found to be contingent on situational characteristics, it remains unclear ...
Pernot, Eli, Roodhooft, Filip
core
The paradoxes of the theory of imprévision in the new French law of contract: a judicial deterrent? [PDF]
, 2019 As part of the reform of the law of contracts,the theory of imprévision is now enshrined in Article 1195 CC of the French Civil Code. The novelty of this article lies essentially in the new judicial power of review. As this paper shows, Article 1195 CC
Pedamon, C., Pedamon, C.
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source