Results 121 to 130 of about 15,871,401 (350)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Integrating services for young children and their families [PDF]
In an effort to improve outcomes for young children and their families, governments in all developed nations are making efforts to integrate services more effectively.
Centre for Community Child Health
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Learning from Asia’s Success Beyond Simplistic ‘Lesson-Making’ [PDF]
Many international organizations, governments and academics concerned with economic development look to Asia’s success, recommending that other poor countries follow similar models and paths of development.
Mike Hobday
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Design of a cooperative problem-solving system for enroute flight planning: An empirical study of its use by airline dispatchers [PDF]
In a previous report, an empirical study of 30 pilots using the Flight Planning Testbed was reported. An identical experiment using the Flight Planning Testbed (FPT), except that 27 airline dispatchers were studied, is described.
Chappel, Sherry +6 more
core +1 more source
Welfare Reform and the Devolution of Decision Making Authority: Changes in Administrative Infrastructure for TANF Implementation [PDF]
, 2005 The growing demand for welfare reform represented a devolution of authority from federal administration and enabled state governments to seek ways to improve efficiency and enhance coordination in managing Temporary Assistance for Needy Families (TANF ...
Chang, Hyun-Joo
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Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Temporary Assistance for Needy Families (TANF): Characteristics of the Cash Assistance Caseload [PDF]
, 2013 [Excerpt] This report examines the TANF cash assistance caseload, focusing on how the composition and characteristics of families receiving assistance have changed over time.
Falk, Gene
core +4 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source