Results 151 to 160 of about 15,871,401 (350)
The Acceptability of Foreign Retail Chains by the Inhabitants of Slovakia
Theory, Methodology, Practice, 2005 Consumer behaviour in choosing purchasing place is one part of reaction to changed sales circumstances after the year of 1989. The paper deals with brief development of retail market in Slovakia having in mind the penetration of foreign retail chains ...
Vladimír Gazda +2 more
doaj
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
ARE FOREIGN DIRECT INVESTMENTS AN INSTRUMENT OF SHIFTING THE MOLDAVIAN ECONOMY TO A SUPERIOR LEVEL OF INTERNATIONAL SPECIALISATION? [PDF]
It is a well known fact that a country or other becomes richer or poorer to a large extent depending on the character of the country’s international specialisation.
Dumitru MOLDOVANU
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The Government and the Financial System : an Overview [PDF]
This paper surveys the relationship between the government and the financial system in Japan, mainly from the viewpoint of financial stocks, to gain an overall perspective and identify where any problems lie.
Kazuhito Ikeo, Yasuo Goto
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Acculturation and sports language. An assessment from three languages
Revista MENDIVE, 2011 This article presents how Russian and Spanish, with so differ ent origins, have been and still is under the influence, specifically in sport terminology, of a third language, English. We offer details about how English arrived at each one of them and how
Liliana Martínez Hernández +1 more
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source