Results 111 to 120 of about 233,902 (342)
Social Change: Conflict and Competition
, 2022 Rima-Maria Rahal, Ilja van Beest
openalex +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Management of active ageing in France in businesses: Some case-studies [PDF]
If some European countries started work on age management long ago, several reports confirmed the urgency and the complexity of age management in France.
Bénédicte Gendron
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Changing organizational culture in terms of information and communications technologies [PDF]
Organizational change can be considered a genuine moment of evolution and development of the entire organization and decision of change is closely related to the company's mission, the objectives that wish to achieve in order to ensure their competitive ...
Daniel Boldureanu +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Revue Internationale Animation, Territoires et Pratiques SocioculturellesL’animation culturelle a connu de profondes transformations au cours des 15 dernières années. Ce dynamisme, nourri par l’essor des technologies de communication, l’évolution des publics et la redéfinition du rôle des politiques publiques, a suscité un ...
Jean-Marie Lafortune +1 more
doaj +1 more source
Measuring trade in value added in the new industrial economy: statistical implications [PDF]
Vertical integration of production processes at international level and the resulting fragmentation of the value chains increasingly question the relevance of traditional trade indicators.
Escaith, Hubert
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source