Results 261 to 270 of about 22,201,636 (348)

Islam et changement social [PDF]

, 1998
openaire  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Propithecus verreauxi demography spanning 40 years at Bezà Mahafaly Special Reserve, southwest Madagascar. [PDF]

Sci Data
Ratsirarson J, Ranaivonasy J, Lawler R, Fiorentino I, Rios N, Richard A.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evolution of treatment for unspecific back pain: From past to future. [PDF]

Tunis Med
Herrera D, Hartard C, Ben Saad H, Montanari Mota L, Alves Dos Santos V, Sinha C, Jedidi R, Hartard D, Khaled S, Hartard S, Hartard M.   +10 more
europepmc   +1 more source

Anthropologie du changement social

Annuaire de l'EHESS, 2010
openaire   +2 more sources

Transitioning to Insulin Analogs in Tunisian Children with Type 1 Diabetes: Efficacy and Safety. [PDF]

Tunis Med
Marzouk A, Lajili M, Ben Yahya I, Thebti R, Ayeb S, Bouaziz A.   +5 more
europepmc   +1 more source

[Factors associated with acceptance of COVID-19 vaccination in the Kokolo health zone in Kinshasa, Democratic Republic of Congo (DRC)]. [PDF]

Med Trop Sante Int
Amisi Kengea L, Masamba Bikoki W, Nsinga Bungiena JC, Kape Kalume JJ.   +3 more
europepmc   +1 more source