Results 291 to 300 of about 233,902 (342)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Deservingness on the Front Lines: How Volunteers Navigate Moral Judgments in Emergency Food Distribution. [PDF]

Can Rev Sociol
Hamdon C.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Codéveloppement d'un programme d'autogestion de la douleur chronique en ligne: un projet de recherche basé sur la conception et axé sur l'engagement des patients. [PDF]

Can J Pain
Marier-Deschenes P, Pinard AM, LeBlanc A.   +2 more
europepmc   +1 more source

Anthropologie du changement social

Annuaire de l'EHESS, 2010
openaire   +2 more sources

Validation de L’échelle Unidimensionnelle D’Estime de Soi de Ducher (ESD): Validation of Ducher's Unidimensional Self-Esteem Scale (SES). [PDF]

Can J Psychiatry
de Chazeron I, Ducher JL, Renoux M, Brousse G, Llorca PM.   +4 more
europepmc   +1 more source

Effects of climate change on the Flemish water system (Belgium) [PDF]

, 2009
De Sutter, Renaat, Ingle, Ruchita
core   +1 more source

The sex effect: the prevalence of sex life reasons for contraceptive discontinuation. A systematic review and meta-analysis. [PDF]

Sex Reprod Health Matters
Zaneva M, Thatte N, Philpott A, Maliwa C, Mills R, Gonsalves L.   +5 more
europepmc   +1 more source