Results 81 to 90 of about 11,809,525 (251)

Animation, pensée critique et praxis

open access: yesRevue Internationale Animation, Territoires et Pratiques Socioculturelles, 2014
L’animation socioculturelle est tour à tour présentée comme une praxis et un vecteur de transformation sociale, voire le moule activiste d’acteurs d’horizons divers. La pensée critique, à l’ère de la mondialisation, de la mutation des structures sociales,
Marc-André Kouakou
doaj   +1 more source

Gouvernance climatique au Bénin : la sécurité alimentaire à l’épreuve du changement climatique

open access: yesRevue des Etudes Multidisciplinaires en Sciences Economiques et Sociales, 2019
Cette recherche tente d’appréhender l’importance de la gouvernance climatique dans la lutte contre l’insécurité alimentaire dans un contexte de changement climatique au Bénin.
Yvette Onibon Doubogan   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Les agricultrices, la famille et le changement social et culturel

open access: yes, 1981
Potier Chantal. Les agricultrices, la famille et le changement social et culturel. In: Cahiers du Centre nantais de recherche pour l'aménagement régional, n°19, 1981. A.T.P. du C.N.R.S.
Potier, Chantal
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Changement social et économie solidaire

open access: yes, 2015
LAVILLE Jean-Louis. « Changement social et économie solidaire : les événements dans le processus de recherche ». In Nouvelle revue de psychosociologie, n° 19, 2015, pp.
Rédaction
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Los Angeles County Social Survey, 1993 (LACSS)

open access: yes, 1993
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core   +1 more source

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