Results 151 to 160 of about 177,628,905 (262)

Airway Emergency in a Primigravida Associated With Paradoxical Vocal Fold Motion and Placental Abruption Leading to Emergent Cesarean Delivery: A Case Report. [PDF]

Am J Case Rep
Bliss EG, Marshall BM, Rose GL, Lemoine NP, Damron JK.   +4 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Maternal Diet During Pregnancy and Offspring Health: Current Evidence on Dietary Patterns, Microbiota, and Developmental Programming. [PDF]

Nutrients
Anton-Păduraru DT, Mîndru DE, Haliţchi COI, Bocec AS, Dorneanu OS, Trofin F, Trandafirescu MF, Sur LM, Mărgineanu CE, Popovici P, Diaconescu C, Luca AC.   +11 more
europepmc   +1 more source

Well-being and inequality [PDF]

An objective and a subjective approach to study well-being is introduced. The objective approach is particularly useful to compare the quality of life of given societies across time and space.
Kohler, Ulrich, Böhnke, Petra
core  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

MRI visualization of maternal pelvic and perineal anatomical changes during the second stage of labor: a feasibility study. [PDF]

Eur Radiol Exp
Maran JC, Ami O, Dao TT, Mage G, Boyer L.   +4 more
europepmc   +1 more source

International Evidence on the Social Context of Well-Being [PDF]

This paper uses the first three waves of the Gallup World Poll to investigate differences across countries, cultures and regions in the factors linked to life satisfaction, paying special attention to the social context. Our principal findings are: First,
John F. Helliwell, Haifang Huang, Christopher P. Barrington-Leigh, Anthony Harris   +3 more
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Ethical Considerations With CFTR Modulator Use in Pregnancy. [PDF]

Pediatr Pulmonol
Sheppard M, Massie J.
europepmc   +1 more source