Results 211 to 220 of about 750,328 (309)

Maintaining Local Adaptation Is Key for Evolutionary Rescue and Long-Term Persistence of Populations Experiencing Habitat Loss and a Changing Environment. [PDF]

Evol Appl
Baiotto T, Guzman LM.
europepmc   +1 more source

USA's Changing Environment of Medical School Enrollments [PDF]

, 1998
Greenberg, Daniel S.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Chaperone-mediated autophagy in fish: A key function amid a changing environment. [PDF]

Autophagy Rep
Schnebert S, Vélez EJ, Goguet M, Dias K, Véron V, García-Pérez I, Radler LM, Cardona E, Fontagné-Dicharry S, Van Delft P, Dittrich-Domergue F, Bernard A, Beaumatin F, Herpin A, Cleveland B, Seiliez I.   +15 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Adapting attentional control settings in a shape-changing environment. [PDF]

Atten Percept Psychophys
Mu Y, Schubö A, Tünnermann J.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Resistome in a changing environment: Hotspots and vectors of spreading with a focus on the Russian-Ukrainian War. [PDF]

Heliyon
Symochko L, Pereira P, Demyanyuk O, Pinheiro MNC, Barcelo D.   +4 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Differential Responses of Bilberry (Vaccinium myrtillus) Phenology and Density to a Changing Environment: A Study from Western Carpathians. [PDF]

Plants (Basel)
Kubov M, Fleischer P, Tomes J, Mukarram M, Janík R, Turyasingura B, Fleischer P, Schieber B.   +7 more
europepmc   +1 more source