Results 41 to 50 of about 3,756,943 (255)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A Review of 2D Lidar SLAM Research

Remote Sensing
Two-dimensional (2D) simultaneous localization and mapping (SLAM) is a key technology for intelligent indoor robots. By using a map generated via SLAM, the robot can navigate and perform specific tasks.
Yingying Ran, Xiaobin Xu, Zhiying Tan, Minzhou Luo   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Simulated self-organization of death by inherited mutations

Anais da Academia Brasileira de Ciências, 2009
An agent-based computer simulation of death by inheritable mutations in a changing environment shows a maximal population, or avoids extinction, at some intermediate mutation rate of the individuals.
Jorge S. Sá Martins, Dietrich Stauffer, Paulo M.C. de Oliveira, Suzana Moss de Oliveira   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Temporal-spatial Evolution of Drought Characteristics at Different Grades in Yulin

Renmin Zhujiang, 2021
Under the background of climate warming and human activities,Yulin city suffers from frequent drought,which has adverse effect on the agriculture,ecological environment and social economy in this area.Although the adverse effects of drought on the Loess ...
KONG Gang, ZHANG Shanliang, WANG Lu, HUANG Shengzhi, BAI Jueying   +4 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

CHANGING LEARNING ENVIRONMENT THROUGH TECHNOLOGY [PDF]

Evolution of E-learning phenomenon exceeded all expectations in recent years.As a result of development of IT&C technologies and, on the other hand, due to support decision-makers at European level, the assimilation of virtual learning platforms in ...
Aleca Ofelia, Mihai Florin, Stanciu Andrei   +2 more
core  

Adaptive development and maintenance of user-centric software systems [PDF]

, 2004
A software system cannot be developed without considering the various facets of its environment. Stakeholders – including the users that play a central role – have their needs, expectations, and perceptions of a system.
Alspaugh, Beynon-Davies, Borgholm, Breitman, Bødker, Claus Pahl, Crnkovic, Dix, Egyed, Grønbæk, Kazman, Kotonya, Kösters, Lee, Lung, Medvidovic, Moisiadis, Nuseibeh, Pahl, Russo, Shaw, Smeaton, Smeaton, Sommerville, Sutcliffe   +24 more
core   +1 more source