Results 181 to 190 of about 3,122,392 (352)

Introducing Vernakalant into Clinical Practice

Arrhythmia & Electrophysiology Review, 2019
Angela JM Hall, Andrew RJ Mitchell
doaj   +1 more source

Mechanosensitive ion channels in intestinal homeostasis and disease. [PDF]

eGastroenterology
Cao Y, Rao Q, Bai X, Li W, Dai H, Xue X, Jiang L, Yang H, Ma N.   +8 more
europepmc   +1 more source

Taming Timing: Testing Side-Channel Resistance on Java Card Platform

Veronika Hanulíková, Petr Švenda
openalex   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

A 128-Channel 0.2-8.2 V Calibrated DAC IC Achieving 0.26-LSB DNL and 0.71-LSB DVO for Photonic Computing. [PDF]

Micromachines (Basel)
Li L, Lv D, Lv J, Li D, Du L, Du Y.
europepmc   +1 more source

Climate change, human activities, and the mid-nineteenth century evolution of the Jingjiang river channel in the Yangtze river's middle reaches

Yang Yuda, Zhengrong Xu, Liu Wei, Han Jianfu   +3 more
openalex   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Ion Channel-Targeting Modulators in Glioma: Pharmacological Advances and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Wu SN, Lin SC, Liutkevičienė R.
europepmc   +1 more source

Macroinvertebrate functional composition along a gradient of hydromorphological restoration effort in a lowland channelized river

Liévin Castelain, Camille Carpentier, Camille Fraudin, Alexandre Peeters, Gisèle Verniers, Eva Mercier, Geoffrey Houbrechts, Patrick Kestemont   +7 more
openalex   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source