Results 51 to 60 of about 56,182 (260)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Interference-Avoid Channel Assignment for Multi-Radio Multi-Channel Wireless Mesh Networks With Hybrid Traffic

open access: yesIEEE Access, 2019
Interference is the main factor that leads to the decrease in network performance in wireless mesh networks (WMNs). In this paper, we propose a load-balance and interference-avoid partially overlapped channels assignment (LBIA-POCA) scheme aiming to ...
Lu Yang   +3 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Channel Assignment Strategy Based on the Sustained-Transmission Rule of Nodes in Cognitive Radio Sensor Network

open access: yesDianxin kexue, 2015
In order to improve the success rate of data packet transmission in heterogeneous and hierarchical cognitive radio sensor network,the nodes were divided into sustained-transmission and non-sustained-transmission conditions.The ways of improving the ...
Xinbin Li   +3 more
doaj   +2 more sources

Comparative performance analysis of subcarrier assignment for real‐time video traffic

open access: yesIET Networks, 2015
The ability to transmit video and carry real‐time multimedia applications such as video‐streaming, video conferencing and mobile TV are considered important to support the viability and survivability of next generation mobile wireless networks. High peak
J. Benita, R. Jayaparvathy
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Optimal channel assignment on dense Wi-Fi networks using Thermodynamic Threshold Accepting

open access: yesEngineering Science and Technology, an International Journal
Channel assignment in Wi-Fi 6 dense networks is a challenging problem which critically impacts the performance of WLAN communications. Although there have been many proposals in the area of IEEE 802.11 channel assignment, LCCS has emerged as the de facto
Marino Tejedor-Romero   +4 more
doaj   +1 more source

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