Results 121 to 130 of about 1,248,788 (338)
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
On the capacity of a discrete, constant channel
Information and Control, 1967 This paper is concerned with an iterative method for calculation of the capacity of a discrete, constant channel. Unlike the standard reference (Muroga 1953), in which Lagrange multipliers are used in the conventional form, the method described is based on techniques of mathematical programming.
Bernd Meister, Werner Oettli
openaire +2 more sources
Capacity of a Simple Intercellular Signal Transduction Channel
, 2013 We model the ligand-receptor molecular communication channel with a discrete-time Markov model, and show how to obtain the capacity of this channel. We show that the capacity-achieving input distribution is iid; further, unusually for a channel with ...
Eckford, Andrew W., Thomas, Peter J.
core +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Computing quantum discord is NP-complete
New Journal of Physics, 2014 We study the computational complexity of quantum discord (a measure of quantum correlation beyond entanglement), and prove that computing quantum discord is NP-complete.
Yichen Huang
doaj +1 more source
The MAPK/ERK channel capacity exceeds 6 bit/hour. [PDF]
PLoS Comput Biol, 2023 Nałęcz-Jawecki P +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
A Semi-Quantum Secret-Sharing Protocol with a High Channel Capacity. [PDF]
Entropy (Basel), 2023 Tian Y +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal +2 more
wiley +1 more source