Results 71 to 80 of about 2,850,266 (283)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

High accuracy channel estimation algorithms for multi-cell joint detection

Tongxin xuebao, 2008
The conventional channel estimation algorithm used in the current TD-SCDMA system can not be expanded to multi-cell joint detection for its low channel estimation accuracy for adjacent cells.
SONG Xiao-qin1, HU Ai-qun1, LI Ke2, XUE Qiang2   +3 more
doaj   +2 more sources

An Improved GOMP Sparse Channel Estimation for Vehicle-to-Vehicle Communications

International Journal of Antennas and Propagation, 2023
Reliable channel estimation is critical for wireless communication performance, especially in vehicle-to-vehicle (V2V) communication scenarios. Aiming at the major challenges of channel tracking and estimating as the highly dynamic nature of vehicle ...
Xin Chen, Xudong Zhang, Yaolin Zhu, Ruiqing Ma   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Efficient model-and-data based channel estimation algorithm

Tongxin xuebao, 2022
For orthogonal frequency division multiplexing (OFDM) systems, a hybrid model and data driven channel estimation algorithm was proposed.Combined with two existing channel estimation methods, including a low complex learning-based channel estimation ...
Kai MEI, Haitao ZHAO, Xiaoran LIU, Jun LIU, Jun XIONG, Baoquan REN, Jibo WEI   +6 more
doaj   +2 more sources

Analysis and Design of Channel Estimation in Multicell Multiuser MIMO OFDM Systems [PDF]

, 2014
This paper investigates the uplink transmission in multicell multiuser multiple-input multiple-output (MIMO) orthogonal frequency-division multiplexing (OFDM) systems. The system model considers imperfect channel estimation, pilot contamination (PC), and
Xu, Peng, Qi, Feng, Wang, Jinkuan, Wang, Jiangzhou   +3 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Low Complexity Hybrid-Field Channel Estimation Based on Simultaneous Weighted OMP Algorithm in Extreme Large-Scale MIMO Systems

IEEE Access
Extreme large-scale multiple-input multiple-output (XL-MIMO) is one of the key technologies for future 6G communications. Channel estimation plays a crucial role in XL-MIMO systems, as accurate Channel State Information (CSI) is essential for effective ...
Huan Huang, Junxin Zhang, Jun Jiang
doaj   +1 more source