Results 61 to 70 of about 1,263,266 (290)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings
Micromachines, 2020 Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and ...
Minako Hirano +6 more
doaj +1 more source
Experimental testbed for seawater channel characterization
, 2016 Shallow seawaters are problematic for acoustic and optical communications. Sensor networks based on electromagnetic (EM) communications are evaluated in this environment.
Cardona, Laura +8 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Cluster Analysis of Pedestrian Mobile Channels in Measurements and Simulations
Applied Sciences, 2019 In wireless communication systems, channels evolve when user terminals move. To further understand channel variation, and especially the evolution of clusters in mobile channels, a set of experiments was designed.
Chao Wang, Jianhua Zhang, Guangzhong Yu
doaj +1 more source
Parametric channel estimation for massive MIMO
, 2017 Channel state information is crucial to achieving the capacity of multi-antenna (MIMO) wireless communication systems. It requires estimating the channel matrix.
Magoarou, Luc Le, Paquelet, Stéphane
core +1 more source
Measuring Method for Lightning Channel Temperature
Scientific Reports, 2016 AbstractIn this paper, we demonstrate the temperature of lightning channel utilizing the theory of lightning spectra and the model of local thermodynamic equilibrium (LTE). The impulse current generator platform (ICGS) was used to simulate the lightning discharge channel, and the spectral energy of infrared spectroscopy (930 nm) and the visible ...
X. Li, J. Zhang, L. Chen, Q. Xue, R. Zhu
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Scalable user selection in FDD massive MIMO
EURASIP Journal on Wireless Communications and Networking, 2021 User subset selection requires full downlink channel state information to realize effective multi-user beamforming in frequency-division duplexing (FDD) massive multi-input multi-output (MIMO) systems. However, the channel estimation overhead scales with
Xing Zhang, Ashutosh Sabharwal
doaj +1 more source
Deep Learning Based NLOS Identification with Commodity WLAN Devices
, 2017 Identifying line-of-sight (LOS) and non-LOS (NLOS) channel conditions can improve the performance of many wireless applications, such as signal strength-based localization algorithms.
Choi, Jeong-Sik +4 more
core +1 more source