Results 271 to 280 of about 18,335 (296)

Development and characterization of an Sf-1-Flp mouse model. [PDF]

JCI Insight
Galvan M, Fujitani M, Heaselgrave SR, Thomas S, Chen B, Lee JJ, Wyler SC, Elmquist JK, Fujikawa T.   +8 more
europepmc   +1 more source

Electrostatic Control of Photoisomerization in Channelrhodopsin 2. [PDF]

Journal of the American Chemical Society, 2021
Channelrhodopsin 2 (ChR2) is the most commonly used tool in optogenetics. Because of its faster photocycle compared to wild-type (WT) ChR2, the E123T mutant of ChR2 is a useful optogenetic tool when fast neuronal stimulation is needed.
Ruibin Liang, Jimmy K. Yu, J. Meisner, F. Liu, T. Martínez   +4 more
semanticscholar   +4 more sources

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Light-gated channelrhodopsin sparks proton-induced calcium release in guard cells

Science, 2023
Although there has been long-standing recognition that stimuli-induced cytosolic pH alterations coincide with changes in calcium ion (Ca2+) levels, the interdependence between protons (H+) and Ca2+ remains poorly understood. We addressed this topic using
Shouguang Huang, Like Shen, M. Roelfsema, Dirk Becker, R. Hedrich   +4 more
semanticscholar   +1 more source

Twisting and Protonation of Retinal Chromophore Regulate Channel Gating of Channelrhodopsin C1C2.

Journal of the American Chemical Society, 2023
Channelrhodopsins (ChRs) are light-gated ion channels and central optogenetic tools that can control neuronal activity with high temporal resolution at the single-cell level.
Keisei Shibata, K. Oda, T. Nishizawa, Y. Hazama, Ryohei Ono, Shunki Takaramoto, R. Bagherzadeh, H. Yawo, O. Nureki, Keiichi Inoue, Hidefumi Akiyama   +10 more
semanticscholar   +1 more source

WormRuler: A software to track body length used to characterize a super red-shifted channelrhodopsin in Caenorhabditis elegans

microPublication Biology, 2022
Manipulation of neuronal or muscular activity by optogenetics or other stimuli can be directly linked to the analysis of Caenorhabditis elegans ( C. elegans ) body length. Thus, WormRuler was developed as an open-source video analysis toolbox that offers
Marius Seidenthal, Dennis Vettkötter, A. Gottschalk   +2 more
semanticscholar   +1 more source

Biophysics of Channelrhodopsin

Annual Review of Biophysics, 2015
Channelrhodopsins (ChRs) are directly light-gated ion channels that function as sensory photoreceptors in flagellated green algae, allowing these algae to identify optimal light conditions for growth. In neuroscience, ChRs constitute the most versatile tools for the light-induced activation of selected cells or cell types with unprecedented precision ...
Franziska Schneider, Peter Hegemann, Christiane Grimm   +2 more
openaire   +3 more sources