Results 11 to 20 of about 17,779 (238)
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE), but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung +6 more
wiley +1 more source
Even at the uttermost ends of the Earth: how seabirds telecouple the Beagle Channel with regional and global processes that affect environmental conservation and socio-ecological sustainability [PDF]
, 2017 Human-wildlife dynamics exhibit novel characteristics in the Anthropocene, given the unprecedented degree of globalization that has increased the linkages between habitats and people across space and time. This is largely caused by transnational mobility
Anderson, Christopher Brian +3 more
core
Arthritis Care &Research, Accepted Article.Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy +9 more
wiley +1 more source
Immune Checkpoint Inhibitor Related Myositis and Associated Triad Overlap Syndrome
Arthritis Care &Research, Accepted Article.Objective Immune checkpoint inhibitor (ICI) myositis is a rare but highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino +9 more
wiley +1 more source
A hierarchical mathematical model for automatic pipelining and allocation using elastic systems [PDF]
, 2018 The advent of FPGA-based accelerators has encouraged the use of high-level synthesis (HLS) for rapid prototyping and design space exploration. In this context, design optimization at behavioral level becomes a critical task for the delivery of high ...
Cortadella, Jordi +1 more
core +1 more source
Advanced Functional Materials, EarlyView.A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu +8 more
wiley +1 more source
Rotten Bananas, Hip Hop Heads, and the American Individual: Teaching Eddie Huang’s Memoir Fresh Off the Boat and Its Tropes of Literacy [PDF]
, 2017 This essay focuses on Fresh Off the Boat as an eminently teachable coming-of-age story, provides critical contexts and directions for teaching this ideologically suggestive text, and sets forth the interpretive argument that the structures and themes of ...
Chen, Wilson C
core +1 more source
Advanced Healthcare Materials, EarlyView.Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady +5 more
wiley +1 more source