Results 191 to 200 of about 153,425 (308)

A Hanks‐type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation

The FEBS Journal, EarlyView.
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima, Dev Sriranganadane, Daiane Laise da Silva, Natália C. Drebes Dörr, Enzo Breviglieri Sichi Mello, Caio Vinicius dos Reis, Rogério Ferreira Lourenço, José Felipe Teixeira da Silva Santos, Anita Salmazo, Brenno Wendler Miranda, Katlin B. Massirer, Rafael M. Couñago, Cristina E. Alvarez‐Martinez   +12 more
wiley   +1 more source

Private funerary chapel (family charnel house), Cemetery of Prazeres, Lisbon, Portugal (J.P. 2776, R.5, Z.30, PRZ, 2024.05.25, PGM07809PP)

de Mendonça, Philippe Gil
openalex   +1 more source

Penetration enhancement effects of topically applied crosslinked hyaluronic acid

International Journal of Cosmetic Science, EarlyView.
Cross‐linked hyaluronic acid (HA) was demonstrated to enhance the topical delivery of a variety of hydrophilic actives into the skin. This phenomenon was observed for both small molecules and macromolecules, the latter of which was analysed with MALDI mass spectrometry imaging (MALDI‐MSI).
Aaron Cohen, Raphael Legouffe, Krystal House, Paul Duhamel, Aurore Tomezyk, Mathieu Gaudin, Junhong Mao, David Bonnel   +7 more
wiley   +1 more source

The Incarnational Aesthetic of David Brown☆

International Journal of Systematic Theology, EarlyView.
Abstract The notion of incarnation has historically been a prominent concept for the acceptance of images and the interpretation of art within Christianity. A contemporary proponent of this line of reasoning about the theological potential of art is David Brown, who builds his theology of culture on the doctrine of incarnation. This article presents an
Filip Taufer
wiley   +1 more source

NC CLASP: the structure and reach of a statewide antibiotic stewardship education program. [PDF]

Antimicrob Steward Healthc Epidemiol
Kistler CE, Thomas ES, Cook E, Doughman D, Enyioha C, Austin CA, Brown MM, Willis ZI, Johnson JW, Khairat S, Sloane PD.   +10 more
europepmc   +1 more source

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Differential roles of Rad18 in repressing carcinogen- and oncogene-driven mutagenesis <i>in vivo</i>. [PDF]

NAR Cancer
Anand JR, Brown BW, Lou J, Gu Q, Yang Y, Droby G, Wu D, Jena A, Xie J, Fedoriw Y, Weissman B, Williams S, Vaziri C.   +12 more
europepmc   +1 more source

Medical Knowledge Integration Into Reinforcement Learning Algorithms for Dynamic Treatment Regimes

International Statistical Review, EarlyView.
Summary The goal of precision medicine is to provide individualised treatment at each stage of chronic diseases, a concept formalised by dynamic treatment regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from clinical data to enhance therapeutic effectiveness.
Sophia Yazzourh, Nicolas Savy, Philippe Saint‐Pierre, Michael R. Kosorok   +3 more
wiley   +1 more source

Using Affirmative Action as a Tiebreaker

Journal of Applied Philosophy, EarlyView.
ABSTRACT We argue in favor of affirmative action. There are two central points to our argument. First, if two or more candidates for a position are matched in competence, then one ought to prefer a candidate from a disadvantaged, disenfranchised, or minority background rather than defer to the outcome of a lottery.
Shalom Chalson, James Bernard Willoughby
wiley   +1 more source

VI - Chapelle pontificale

, 2002
openaire   +1 more source