Results 101 to 110 of about 2,777,537 (306)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Strategi Pengembangan Karakter Leadership Siswa melalui Program Berbasis Pembinaan

J-MPI (Jurnal Manajemen Pendidikan Islam)
The principal’s strategy in shaping student character, especially leadership character, is very important to create a generation of leaders with quality and integrity.
Triana May Latul Anisa, Devi Pramitha
doaj   +1 more source

The Development of Charater Education Model to Improve Students’ Academic Independence in Islamic Boarding School in Sinjai District, Indonesia. [PDF]

, 2016
Abstrak The Objektive of this research and development is to crate a description of the operational model of character education amnd to determine the effectiveness of a character education model in ebhancing students’ academic independence.
Bachri Thalib, Syamsul, Ismail, Sulaeman, dkk   +1 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Final proposal to encode the Pahawh Hmong script in the UCS [PDF]

, 2012
This is a proposal to encode the Pahawh Hmong script in the international character encoding standard Unicode. Pahawh Hmong was published in Unicode Standard version 7.0 in June 2014. The script is said to have been devised in the latter half of the 20c.
Everson, Michael
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integrating Islamic Moral Values into Holistic Education: A Systematic Character Development Model in Indonesian Junior High Schools

Journal of Islamic Education Research
This study aims to examine how Islamic moral values are systematically integrated into holistic education through a structured character development model in Indonesian junior high schools.
Ifa Maulida, Benny Prasetiya, Muhammad Faizal A Ghanib   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fearless: Ally Siegel

, 2014
Encouraging and mentoring young minds, consistently finding new ways to use her love of climbing and adventure to promote character and leadership development, and always ready for the next big challenge, Ally Siegel ’16 fearlessly pushes herself to ...
Siegel, Alexandra M.
core