TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Electrophysiological activity predicts children's reading ability through orthographic awareness: Evidence from a cross-sectional and longitudinal study. [PDF]
Zhang M +5 more
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Deciphering the molecular origin of the 19.3 eV electronic excitation energy of H<sub>3</sub>. [PDF]
Toldo JM +4 more
europepmc +1 more source
Elastic Energy Storage in Al-Al<sub>4</sub>C<sub>3</sub> Composites: Effects of Dislocation Character and Interfacial Graphite Formation. [PDF]
Santos Beltrán A +8 more
europepmc +1 more source
Early ethics: Exploring moral intuition and maternal Influence in preschool children. [PDF]
Jean-Tron MG +7 more
europepmc +1 more source
Modular synthesis of benzothiophene-fused pentalenes reveals substituent-dependent antiaromaticity. [PDF]
Isogai R, Yasui K, Fukazawa A.
europepmc +1 more source
Comparative anatomy of the thoracic muscles of bees (Hymenoptera: Apoidea). [PDF]
Meira OM, Almeida EAB.
europepmc +1 more source
Character-level linguistic biomarkers for precision assessment of cognitive decline: a symbolic recurrence approach. [PDF]
Mekulu K, Aqlan F, Yang H.
europepmc +1 more source

