Results 231 to 240 of about 2,777,537 (306)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

The Legal Regulation of Cybercrimes related to Character Assassination under the Jordanian and French Legislation. [PDF]

F1000Res
Al-Rai A, Imad D, Khater M.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

I am a child, i learn through play; play-based character education. [PDF]

Front Psychol
Görün L, Baba Kaya H, Alper R, Koç M, Çelen A, Akpınar S, Pepe Ş, Eskicioǧlu YE.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

LICS: Locating Inter-Character Spaces for Multilingual Scene Text Detection. [PDF]

Sensors (Basel)
Su PC, Lee MC, Tung YT, Chen LZ, Han CH, Kuo TY.   +5 more
europepmc   +1 more source

The Good Surgeon: A Pilot Program for Flourishing in Surgical Residency. [PDF]

Ann Surg Open
Howell TC, Eberly JB, Stonerook E, Stanulis R, Edwards NC, Jo KK, Neff LP, Zeller KA, Antiel RM.   +8 more
europepmc   +1 more source

Latent profiles in the 5 C positive youth development framework: insights into well-being, mental health, and behavioral outcomes. [PDF]

BMC Psychol
Rovis D, Novak M, Gacal H, Maglica T, Mihic J, Sutic Barbaric L, Vrdoljak G.   +6 more
europepmc   +1 more source