Results 231 to 240 of about 2,787,776 (305)

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Elastic Energy Storage in Al-Al<sub>4</sub>C<sub>3</sub> Composites: Effects of Dislocation Character and Interfacial Graphite Formation. [PDF]

open access: yesMaterials (Basel)
Santos Beltrán A   +8 more
europepmc   +1 more source

Early ethics: Exploring moral intuition and maternal Influence in preschool children. [PDF]

open access: yesPLoS One
Jean-Tron MG   +7 more
europepmc   +1 more source

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