Results 81 to 90 of about 2,777,537 (306)

Rhetorical Self-Fashioning in Aramburu: A Contemporary Take on Cervantine Techniques [PDF]

open access: yes, 2019
 In Cervantes’ Don Quijote (1605), Dulcinea does not participate in any dialogue, and yet still appears a vivid character as real as the other female characters who do speak in the novel.
Posey, Alison
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Adaptive recommendation of student-created micro-lessons based on learning style and knowledge-level modeling

open access: yesDiscover Education
Intelligent tutoring system (ITS) are increasing in both intelligence and precision over time, as the demand for personalization grows and procedures become more standardized.
Doniyorbek Ahmadaliev   +5 more
doaj   +1 more source

The Phenomenon of Character Development in a Distance Education Course [PDF]

open access: yes, 2010
Rarely are character development-related aims espoused by higher education reflected in the design and delivery of distance education programs. Further, literature exploring the character development aspects of distance education is sparse.
Johnson, Michael C.   +2 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

THE DEVELOPMENT OF THE MAIN CHARACTER INMITCH ALBOM’S THE FIVE PEOPLE YOU MEET IN HEAVEN [PDF]

open access: yes, 2016
The Five People You Meet in Heaven is a very unique and interesting novel written by a well-known author and script writer Mitch Albom. This novel tells the story about a journey of a man in his search for the purpose of his existence in the afterlife ...
Nugraha, Rio Eka
core   +2 more sources

How can neuroscience contribute to moral philosophy, psychology and education based on Aristotelian virtue ethics? [PDF]

open access: yes, 2016
The present essay discusses the relationship between moral philosophy, psychology and education based on virtue ethics, contemporary neuroscience, and how neuroscientific methods can contribute to studies of moral virtue and character. First, the present
Han, Hyemin
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Bhima in Postmodern Meaningfulness [PDF]

open access: yes, 2012
The Bhīma character is the strongest character among the Panca Pandawas in the Mahabharata, this perception has been held since the classical age up to now, which made Bhīma becomes a cultural icon of the Archipelago.
I NYOMAN , LINGGIH
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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