Results 181 to 190 of about 8,125,392 (387)
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Character Education and Students Social Behavior [PDF]
In an educational environment, in the form of character education program has been done both formally and informally. It's intended as one of the supporting ideas for follow-up in the form of design activities. Character education should basically refers
Kamaruddin, S. A. (Syamsu)
core
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Model Pendidikan Karakter Untuksekolah Menengah Kejuruan (Smk) di Kota YOGYAKARTA [PDF]
This study aims to determine the manufacture of the formulation of a model for charactereducation Vocational School (SMK) in Yogyakarta by using norms and local knowledge of Yogyakarta.This research is a qualitative descriptive study.
dan Rahmah Tyasari, Untung Kurniawan, Doni Sarosa
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
THEORETICAL ASPECTS OF FINANCING HIGHER EDUCATION [PDF]
This article deals with theoretical aspects of financing higher education, to which primarily belongs the issue of the character of education as a good, but also particular reasons for the state intervention to the education and a question about student ...
Ing. Daša Vališová
core
Nation Character Building through Physical Education: Lesson Learnes from 2013 Indonesian National Curriculum [PDF]
Wawan Sundawan Suherman
openalex +1 more source

