Results 41 to 50 of about 169,983 (336)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

FEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon, Juho Choi, Youngin Roh, Eunbin Lee, Luigie Villamante, Myung‐Hee Kwon   +5 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Character Education Innovation in Citizenship Education Learning in Developing Students' Character

Basica
Pembelajaran  Pendidikan Kewarganegaraan (PKn) mempunyai kedudukan yang penting dalam upaya mempersiapkan Peserta didik menjadi warga Negara yang memiliki komitmen kuat dan konsisten untuk mempertahankan NKRI, oleh karena itu pembelajaran PKn diarahkan ...
Moh. Hayatul Ikhsan
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

The impact of religious education in mitigating the effects of family environment on students' mental health

Frontiers in Education
The mental health of students is a significant issue, particularly in the face of the difficulties posed by a complicated familial setting. The significance of religious education in mitigating the impact of the family environment on students' mental ...
Sadam Fajar Shodiq, Anisa Dwi Makrufi, Asep Dahliyana, Nadira Putri Valencia, Fadhila Aisyah Nurunisa, Limason Goselfa   +5 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Al-Zarnuji’s Character Concept in Strengthening Character Education in Indonesia

Jurnal Pendidikan Islam, 2019
This study aims to find the relevance and contextualization of the thoughts of al-Zarnuji's character in the present context especially in relation to strengthening character education in Indonesia.
Djeprin E. Hulawa
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Survey data of internet skills, internet attitudes, computer self-efficacy, and digital citizenship among students in Indonesia

Data in Brief, 2021
Dataset provides wide measurement data on internet skills, internet attitudes, computer self-efficacy of the students related to the digital citizenship in Indonesia.
Wibowo Heru Prasetiyo, Noor Banu Mahadir Naidu, Beti Indah Sari, Rochman Hadi Mustofa, Naillysa Rahmawati, Gilang Pambudi Adi Wijaya, Obby Taufik Hidayat   +6 more
doaj  

Intrinsic motivation, Need for cognition, Grit, Growth Mindset and Academic Achievement in High School Students: Latent Profiles and Its Predictive Effects [PDF]

arXiv, 2022
Recent efforts to identify non-cognitive predictors of academic achievement have especially focused on self-constructs, whose measurement is concerned with a specific domain (e.g., mathematics). However, other important factors, such as character and motivation, have received less attention.
arxiv