Results 141 to 150 of about 2,522,488 (296)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Narratives on Career Development: A Writing Guide for Academics

open access: yes
These are inspirational guidelines for writing professional career narratives in the EUR Development cycle for academics. These guidelines provide additional support for those undergoing this process.
Recognition & Rewards
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Narratives on Career Development: A Reading Guide for Supervisors

open access: yes
These guidelines support the integration of professional career narratives within the EUR Development cycle for academic staff. They are designed to assist academic staff who hold supervisory roles. The guidelines can be used before or during Development
Recognition & Rewards
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A benchmark dataset for printed Meitei/Meetei script character recognition. [PDF]

open access: yesData Brief, 2022
Khuman YLK   +4 more
europepmc   +1 more source

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