Results 201 to 210 of about 107,810 (260)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Character recognition — A review

Pattern Recognition, 1990
The machine replication of human reading has been the subject of intensive research for more than three decades. A large number of research papers and reports have already been published on this topic. Many commercial establishments have manufactured recognizers of varying capabilities.
V K Govindan
exaly   +3 more sources

Approaches to chinese character recognition

Pattern Recognition, 1976
Abstract Work on the recognition of Chinese characters is reviewed. All of this work has been reported in just the last nine years, and most of it since 1970. The topics covered are: printed Chinese Character Recognition—Half a dozen groups have tackled this problem, using methods as varied as syntactic description, projection profiles, template ...
William Stallings
exaly   +3 more sources

CHARACTER RECOGNITION

BSSS Journal of Computer, 2022
Character recognition has numerous applications namely postal addresses, bank check amounts, documents, number plates, etc. Development of a recognition system is an emerging need for digitizing handwritten documents that use Tamil characters. Therefore, we created a prediction model to recognize Tamil characters, the model works based on the Deep ...
S Narmatha   +3 more
openaire   +1 more source

Online Character Recognition

Third International Conference on Information Technology and Applications (ICITA'05), 2005
Data entry using a pen forms a natural, convenient interface especially for handheld devices, which are very common now. The large number of writing styles and the variability between them makes the problem of writer-independent handwriting recognition a challenging pattern recognition problem.
Suneeta Agarwal, Vikas Kumar
openaire   +1 more source

On Thai character recognition

Proceedings of ICNN'95 - International Conference on Neural Networks, 2002
Presents a two-stage classification procedure for the recognition of Thai characters. Two classifiers are used to initially classify the characters into different groups and then to classify the characters within each group. Both a backpropagation multi-layered perceptron and a discriminant analysis technique, called penalised discriminant analysis ...
Olivier Y. de Vel   +2 more
openaire   +1 more source

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