Results 61 to 70 of about 14,029 (259)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Colour Perception Graph for Characters Segmentation

open access: yes, 2014
Characters recognition in natural images is a challenging problem, as it involves segmenting characters of various colours on various background. In this article, we present a method for segmenting images that use a colour perception graph. Our algorithm is inspired by graph cut segmentation techniques and it use an edge detection technique for ...
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Character Segmentation in Brahmi Script: Object Detection and KNN Fusion Approach

open access: yesInternational Journal of Computational Intelligence Systems
Automated word recognition has seen significant advancements, and character segmentation remains a crucial step in this process. Although several studies have focused on the segmentation of popular modern scripts, there has been relatively little ...
Neha Gautam, Soo See Chai
doaj   +1 more source

A fuzzy approach for segmentation of touching characters

open access: yesCoRR, 2016
The problem of correctly segmenting touching characters is an hard task to solve and it is of major relevance in pattern recognition. In the recent years, many methods and algorithms have been proposed; still, a definitive solution is far from being found. In this paper, we propose a novel method based on fuzzy logic.
Giuseppe Airò Farulla   +2 more
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Enhanced technique for Arabic handwriting recognition using deep belief network and a morphological algorithm for solving ligature segmentation

open access: yesETRI Journal, 2018
Arabic handwriting segmentation and recognition is an area of research that has not yet been fully understood. Dealing with Arabic ligature segmentation, where the Arabic characters are connected and unconstrained naturally, is one of the fundamental ...
Nada Essa   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Stroke‐Seg: A deep learning‐based framework for chinese stroke segmentation

open access: yesIET Image Processing
Chinese stroke segmentation is a crucial and challenging task for various downstream applications such as font generation, aesthetic evaluation etc.
Xinyu Gong   +3 more
doaj   +1 more source

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