Results 71 to 80 of about 50,698 (283)

Direct and Mediated Effects of a Social-Emotional and Character Development Program on Adolescent Substance Use [PDF]

, 2012
Mitigating and preventing substance use among adolescents requires approaches that address the multitude of factors that influence this behavior. Such approaches must be tested, not only for evidence of empirical effectiveness, but also to determine the ...
Joseph Day, Day, Joseph, Lewis, Kendra M., DuBois, David L., Samuel Vuchinich, Flay, Brian R., Schure, Marc B., David L. DuBois, Bavarian, Niloofar, Acock, Alan, Silverthorn, Naida, Kendra M. Lewis, Niloofar Bavarian, Alan Acock, Frank J. Snyder, Marc B. Schure, Snyder, Frank J., Peter Ji, Brian R. Flay, Vuchinich, Samuel, Ji, Peter, Naida Silverthorn   +21 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

University Students’ Character Strengths and Their Impact on Quality Education in Higher Education

Education Sciences
Character strengths are the positive personality traits essential for a meaningful life. Recognising and applying character strengths is crucial to becoming high-quality learners.
Thet Thet Mar, Balqees Rashid Suleiman AL Mandhari, Mária Hercz, Ahmed Said AlGhdani   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Exploring the role of character strengths in enhancing well-being of adolescents

Rozprawy Społeczne
The field of positive psychology has historically centered on the concept of character strengths as a pivotal factor in comprehending a fulfilling life.
Sher Singh, Manju Manju
doaj   +1 more source

Preliminary Study: Exploring the Perception and Experiences of Using Character Strengths in Student Teachers [PDF]

Revista de Știinţe Educaţiei
In order to empower and well prepare student teachers for their future roles, integrating character strengths into their personal development and academic pursuits is crucial.
Thet Thet MAR, Mária HERCZ
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Relationship between character strengths and personality traits

Estudos de Psicologia (Campinas)
The objective of this study was to determine which Character Strengths can be predicted by Personality traits using the instruments Forças de Caráter (Character Strengths Scale) and Bateria Fatorial de Personalidade (Factor Personality Questionnaire).
Ana Paula Porto NORONHA, Roberta Ramazotti Ferraz de CAMPOS   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Strengths-Based Approach in Vocational Instructor Education: Exploring Character Strengths of Trainees

Education Sciences
Vocational education and training (VET) plays a vital role in sustaining labour market competitiveness and supporting social cohesion, with vocational instructors holding a decisive role in transmitting occupational expertise and shaping the professional
Anetta Bacsa-Bán, Gizella Cserné Adermann, Mladen Bošnjaković   +2 more
doaj   +1 more source