Results 221 to 230 of about 910,708 (274)

Correction: Temporal characterisation and electrophysiological implications of TBI-induced serine/threonine kinase activity in mouse cortex. [PDF]

Cell Mol Life Sci
Gallagher C, Mittmann T.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Characterisation of the Novel <i>Cutibacterium acnes</i> Phage KIT09 and First Report of CRISPR-Cas-Independent Bacteriophage Resistance in Phylotype IA1. [PDF]

Int J Mol Sci
Nguyen PD, Nakanishi K, Nguyen HP, Nguyen HV, Kitao M, Yoshimoto M, Kamei K.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Erratum: "Detailed characterisation of the tuberculosis epidemic in Western Sydney: a descriptive epidemiological study" Sophie Norton, Shopna K. Bag, Jin-Gun Cho, Neil Heron, Hassan Assareh, Laila Parvaresh, Stephen Corbett and Ben J. Marais. <i>ERJ Open Res</i> 2019; 5: 00211-2018. [PDF]

ERJ Open Res
europepmc   +1 more source

Development of a portable avian influenza virus characterisation system: bringing the inside-out. [PDF]

Sci Rep
Low YS, Jauregui R, Calcott B, Wilson A, Gias E, Johnston H, Bueno R, Dewar ML, O'Keefe J, McCulley M.   +9 more
europepmc   +1 more source

Characterisation report

Led by GEO under Task 1.2, the report will include information on the collected data and samples regarding geofluid, temperature, geology, rheology, drilling mud for analysis and characterisation. The results of the analysis will be used to formulate representative geothermal drill environment which will be used to set up the simulated laboratory ...
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Specific effects on the reproductive function including fertility relevant for cumulative risk assessment of pesticide residues. [PDF]

EFSA J
European Food Safety Authority (EFSA), Angeli K, Cavelier A, Coja T, Crivellente F, Lanzoni A, Mohimont L, Nepal M, Nikolopoulou D, Terron A, Castoldi AF.   +10 more
europepmc   +1 more source