Results 151 to 160 of about 3,459,091 (319)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Semiampleness For Calabi-Yau Surfaces In Positive And Mixed Characteristic

open access: yes
In this note, we prove the semiampleness conjecture for Kawamata log terminal Calabi-Yau (CY) surface pairs over an excellent base ring. As applications, we deduce that generalized abundance and Serrano's conjecture hold for surfaces.
Stigant, Liam, Bernasconi, Fabio
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Characteristic scales in supersonic combustion

open access: yes, 2013
The characteristic length scales in supersonic combustion and the related influence factors were calculated and analyzed. In addition, using the hydrogen, ethylene and kerosene as fuels, the operating range of scramjet under the practical flight ...
Li XP(李晓鹏)   +2 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

The study of the characteristic polynomial of graphs

open access: yes, 2011
碩士假設A是n階方陣,A的特徵多項式為p(A,x)=det(xI-A),其中I是n階單位方陣。令G為一含有n個點的簡單圖且A(G)為圖G的鄰接矩陣, 我們稱A(G)的特徵多項式為G的特徵多項式,記為p(G,x)=det(xI-A(G)),其中I是n階單位方陣。 在本論文中我們直接計算出完全圖與星圖的特徵多項式,對於路徑與迴圈我們可得其遞迴關係式;由前面的計算我們得到行列式的化簡與圖之間的關係,推導出圖中含有degree 1的點或含有degree 2的點及含有一個橋的特徵多項式 ...
李明峯; Li, Ming-Feng
core  

THE EVALUATION OF CHARACTERISTICS OF TRAFFIC FLOW IN THE MOST MAJOR CITIES WITH TAKING INTO ACCOUNT THE NETWORK PARKING

open access: yesNauka ta progres transportu, 2008
The approach to an estimation of characteristics of transport traffic streams in the largest cities is considered taking into account network modelling which contrary to existing ones allows expecting characteristics of the traffic with account of ...
M. O. Hryhorov   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

RELATION BETWEEN FUNCTION AND FORM IN VACUUM CLEANERS DESIGN

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
The paper analyses how robotic vacuum cleaner works, describing their cleaning capabilities and additional features. The paper illustrates advantages of using robotic vacuum cleaners that have intelligent programming and a vacuum cleaning system, the ...
Stefan Radu
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Home - About - Disclaimer - Privacy