Results 201 to 210 of about 2,613,486 (269)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Atypical Follicular-Pigmentary Variant of Hailey-Hailey Disease: A Diagnostic Dilemma. [PDF]

Clin Case Rep
Shah S, Shrestha J, Baniya R, Bhusal M, Pradhan K, Maharjan R.   +5 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The "Galaxy Sign" in Lung Cancer Screening: A Benign Mimic of Malignancy. [PDF]

Cureus
Aggarwal R, Aulakh G, Rahman M, Chaudri M, Azam A.   +4 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Serum sST2 and MR-ProADM in pediatric acute rheumatic fever: association with cardiac involvement and clinical risk stratification. [PDF]

Front Pediatr
Altınok EI, Ertürk EY, Bayrak T, Yapar Gümüş C, Bayrak A, Kasar T.   +5 more
europepmc   +1 more source

Dermatoscopic Features of Hyperpigmented Dermatoses. [PDF]

Clin Cosmet Investig Dermatol
Hua Y, Xie B, Shen Y, Song X.
europepmc   +1 more source

Functional brain network organization during the 40-Hz auditory steady-state response in children with and without autism spectrum disorder. [PDF]

Front Psychiatry
Yasumoto M, Miyagishi Y, Hirosawa T, Ono Y, Soma D, Osaka Y, Kameya M, Yuasa K, Sano M, Takeuchi R, Niu Y, Yoshimura Y, Shiota Y, Tanaka S, Hasegawa C, Kikuchi M.   +15 more
europepmc   +1 more source

Design of a 5G millimeter-wave wideband high-gain metamaterial-based antenna. [PDF]

Sci Rep
Osama I, Elhefnawy M, Yahya A.
europepmc   +1 more source

Complementary ROC-Derived Indices for Screening Improper Expression Profiles in RNA-Seq Differential Expression Analysis. [PDF]

Balkan Med J
Başol Göksülük M, Öztürk E, Erkorkmaz Ü, Deveci Özkan A, Kepenek HF, Göksülük D.   +5 more
europepmc   +1 more source