Results 41 to 50 of about 294,141 (201)

A Weighted Estimate for the Square Function on the Unit Ball in $\C^n$

open access: yes, 2007
We show that the Lusin area integral or the square function on the unit ball of $\C^n$, regarded as an operator in weighted space $L^2(w)$ has a linear bound in terms of the invariant $A_2$ characteristic of the weight.
Brett D. Wick   +16 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Discovering the manifold facets of a square integrable representation: from coherent states to open systems

open access: yes, 2018
Group representations play a central role in theoretical physics. In particular, in quantum mechanics unitary --- or, in general, projective unitary --- representations implement the action of an abstract symmetry group on physical states and observables.
Aniello, Paolo
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Donaldson-Witten theory and indefinite theta functions

open access: yes, 2017
We consider partition functions with insertions of surface operators of topologically twisted N=2, SU(2) supersymmetric Yang-Mills theory, or Donaldson-Witten theory for short, on a four-manifold.
Korpas, Georgios, Manschot, Jan
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bounds for Calder\'on-Zygmund operators with matrix $A_2$ weights

open access: yes, 2017
It is well-known that dyadic martingale transforms are a good model for Calder\'on-Zygmund singular integral operators. In this paper we extend some results on weighted norm inequalities to vector-valued functions.
Pott, Sandra, Stoica, Andrei
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Simplified Game for Resolution of Singularities [PDF]

open access: yes, 2014
We will describe a combinatorial game that models the problem of resolution of singularities of algebraic varieties over a field of characteristic zero.
Schicho, Josef
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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