Results 101 to 110 of about 4,452,190 (289)

Exact solution and its pertinent numerical methodology for wave equation subject to local boundary or nonlocal integral conditions

Boundary Value Problems
In this paper, we propose exact solution as well as an efficacious numerical method for the wave equation subject to local boundary or nonlocal integral conservation conditions.
Yao-Hsin Hwang, Pi-Yen Lin
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Characteristic Description and Statistical Model-Based Method for Sea Clutter Modeling

Remote Sensing
The modeling and analysis of sea clutter are of great significance in radar target detection studies in marine environments. Sea clutter typically exhibits non-Gaussian characteristics and spatiotemporal correlations, posing challenges for modeling ...
Huafeng He, Zhen Li, Xi Zhang, Jianguang Jia, Yaomin He, Yongquan You   +5 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A New Distance-Type Fuzzy Inference Method Based on Characteristic Parameters

Mathematics
Reasoning is a cognitive activity that leverages knowledge to generate solutions to problems. Knowledge representations in the brain require both symbolic and graphical information since visual information is figurative and conveys a large amount of ...
Shuoyu Wang
doaj   +1 more source

The Method of Characteristics

, 2022
Differential equations, in particular partial differential equations, are used to mathematically describe many physical phenomenon. The importance of being able to solve these types of equations can therefore not be overstated. This thesis is going to elucidate one method, the method of characteristics, which can in some cases be used to solve partial ...
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Self-dual electrodynamics via the characteristic method: relativistic and Carrollian perspectives

Journal of High Energy Physics
Electric-magnetic duality plays a pivotal role in understanding the structure of nonlinear electrodynamics (NED). The Gaillard-Zumino (GZ) criterion provides a powerful constraint for identifying self-dual theories.
Bin Chen, Song He, Jue Hou
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source