Results 231 to 240 of about 17,389,636 (280)

Pore structure and fractal characteristics of deep shale gas reservoirs in the Western Chongqing block, Sichuan Basin. [PDF]

PLoS One
Fang F, He S, Zhang J, Li X, Zhang H, Chang Y, Li X.   +6 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Erratum in: Prevalence and Characteristics of Myopia in Adult Non-Human Primates in Southwest China. [PDF]

Transl Vis Sci Technol
europepmc   +1 more source

Geochemical Characteristics of Coalbed Methane and Its Multifactor Control in High-Rank Coal Reservoirs, Southern Qinshui Basin, China. [PDF]

ACS Omega
Wu F, Zhang S, Zhang X, Li P, Xu X, Ji S, Wang Z, Hao D, Guo J, Bi X.   +9 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Investigating the scale effect on strength and failure mechanism of roadway surrounding rock. [PDF]

Sci Rep
Wu J, Xie F, Wang Y.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Epidemiology and Associated Factors of Superimposed Preeclampsia in Pregnant Women With Chronic Hypertension: A Retrospective Multicenter Cohort Study. [PDF]

J Pregnancy
Han-Idhikul A, Kongwattanakul K, Komwilaisak R, Saksiriwuttho P, Chaiyarach S, Duangkam C, Chantanavilai S, Thepsuthammarat K.   +7 more
europepmc   +1 more source

Baseline metabolite profiles predict the glucose-lowering efficacy of exenatide in patients with type 2 diabetes. [PDF]

Metabol Open
Le Y, Yang J, Wu Q, Li F, Fu W, Xiao W, Wang H, Hong T, Wei R.   +8 more
europepmc   +1 more source