Results 191 to 200 of about 10,699,688 (385)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

AI and Robotics Advancement in Analytical Mineral Characterization and Mining Processes: A Review and Research Trends Analysis. [PDF]

Top Curr Chem (Cham)
Mkhohlakali A, Toona MP, Mogashane T, Rampfumedzi T, Madzivha P, Letsoalo MR, Ntsasa N, Sehata J, Mukwevho N, Ncedo T, Mabowa MH, Tshilongo J.   +11 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

CONTRIBUTIONS OF DIGITAL IMAGE ANALYSIS TO SEDIMENTARY ROCK CHARACTERIZATION

, 2018
José Agnelo Soares, Paula Rayane Lopes de Andrade, Juliana Trajino Batista   +2 more
openalex   +2 more sources

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.

Cell, 2017
A. G. Robertson, Jaegil Kim, H. Al-Ahmadie, J. Bellmunt, Guangwu Guo, A. Cherniack, T. Hinoue, P. Laird, K. Hoadley, Rehan Akbani, Mauro A. A. Castro, E. Gibb, R. Kanchi, D. Gordenin, S. Shukla, F. Sánchez-Vega, D. Hansel, B. Czerniak, V. Reuter, X. Su, B. Carvalho, Vinicius S. Chagas, K. Mungall, S. Sadeghi, C. Pedamallu, Yiling Lu, L. Klimczak, Jiexin Zhang, Caleb Choo, A. Ojesina, S. Bullman, K. Leraas, T. Lichtenberg, Catherine J. Wu, N. Schultz, G. Getz, M. Meyerson, G. Mills, D. McConkey, J. Weinstein, D. Kwiatkowski, S. Lerner, Monique Albert, I. Alexopoulou, Adrian Ally, T. Antic, M. Aron, M. Balasundaram, J. Bartlett, S. Baylin, Allison Beaver, I. Birol, L. Boice, M. Bootwalla, Jay Bowen, R. Bowlby, Denise Brooks, B. Broom, W. Bshara, E. Burks, F. Cárcano, R. Carlsen, B. Carvalho, A. Carvalho, E. Castle, Patrick Castro, J. Catto, D. Chesla, E. Chuah, Sudha Chudamani, V. Cortessis, S. Cottingham, D. Crain, Erin E. Curley, S. Daneshmand, J. Demchok, Noreen Dhalla, H. Djaladat, J. Eckman, Sophie C. Egea, J. Engel, Ina Felau, M. Ferguson, J. Gardner, J. Gastier-Foster, M. Gerken, C. Gomez-Fernandez, Jodi Harr, A. Hartmann, Lynn M. Herbert, T. Ho, R. Holt, C. Hutter, Steven J. M. Jones, M. Jordá, R. Kahnoski, K. Kasaian, Phillip H. Lai, B. Lane, Jia Liu, Laxmi Lolla, Y. Lotan, Fabiano R Lucchesi, Yussanne Ma, R. Machado, D. Maglinte, D. Mallery, M. Marra, S. Martin, Michael Mayo, A. Meraney, A. Moinzadeh, Richard A. Moore, Edna M. Mora Pinero, S. Morris, C. Morrison, A. Mungall, J. Myers, R. Naresh, P. O’Donnell, D. Parekh, J. Parfitt, J. Paulauskis, R. Penny, T. Pihl, S. Porten, Mario E. Quintero-Aguiló, N. Ramirez, W. Rathmell, K. Rieger-Christ, Charles Saller, A. Salner, G. Sandusky, C. Scapulatempo-Neto, J. Schein, A. Schuckman, N. Schultz, C. Shelton, T. Shelton, J. Simko, Parminder Singh, Payal Sipahimalani, N. Smith, H. Sofia, A. Sorcini, M. Stanton, G. Steinberg, R. Stoehr, T. Sullivan, Qiang Sun, Angela Tam, R. Tarnuzzer, Katherine Tarvin, H. Taubert, N. Thiessen, L. Thorne, Kane Tse, Kelinda Tucker, D. V. Berg, K. V. Kessel, S. Wach, Yunhu Wan, Zhining Wang, D. Weisenberger, L. Wise, Tina Wong, Ye Wu, Liming Yang, L. A. Zach, J. Zenklusen, Jiashan Zhang, E. Zmuda, E. Zwarthoff   +172 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cross-Sectional Evaluation of Medical Disinformation Safeguards in Consumer-Facing Large Language Model Platforms. [PDF]

JMIR Infodemiology
Modi ND, Alex CA, Awaty AA, Menz BD, Bacchi S, Gradon KT, Logan JM, Rowland A, Kalisch Ellett L, McKinnon RA, Wiese MD, Sorich MJ, Hopkins AM.   +12 more
europepmc   +1 more source

Characterization and Pathogenicity of Haemophilus paragallinarum Serotype C in Local Chickens of Taiwan.

, 1996
James A. Lin, Chin-Ling Shyu, Takeshi Yamaguchi, Masami Takagi   +3 more
openalex   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Towards improving the PF1B beamline <i>McStas</i> model through simulations of a beam characterization experiment. [PDF]

J Appl Crystallogr
Desalme C, Pioquinto J, Czamler V, Baeßler S, Bodek K, Nesvizhevsky V, Rozpędzik D, Schreiner K, Soldner T.   +8 more
europepmc   +1 more source